About BioDoks


I, Dr. Stefanie Flunkert, founded BioDoks 2020 in the midst of Corona crisis. I studied Biology with the focus neuroscience, behavior, physiology and physiological psychology at the University of Bielefeld, Germany. Afterwards, I performed my PhD thesis at the Max Planck Institute for Brain Research, Frankfurt/Main with the academic supervision by the TU Darmstadt. After graduation, I moved to the US and worked for 5 years as PostDoc at the Lombardi Cancer Center, Georgetown University, Washington, DC.

For the last 12 years and ongoing, I work for the preclinical CRO QPS Austria GmbH, Grambach, Austria, writing the scientific content of manuscripts, posters, grant applications, marketing materials etc. and edit the theses of students.

For 8 years, I was animal welfare officer of the AAALAC-accredited animal facility of QPS Austria. Today, I still remain animal welfare officer deputy. During this time, I wrote more than 150 animal experiment applications / animal protocols and related documents such as interim and final reports.

 

Areas of expertise

Neuroscience, neurodegenerative and rare diseases, physiology, behavioral science, tumor biology, animal models and welfare, preclinical research.

Methods: behavioral tests, animal treatments and surgeries, in vivo imaging, tissue sampling, histology, molecular methods for analysis of DNA, RNA and protein, cell culture.

 

Number of edited theses

  • 10+ PhD theses
  • 15+ Master theses
  •   6 Bachelor theses

 

List of publications

 

  1. Trovo L, Vaucher A, Pan Y, Steiner P, Flunkert S, Fleming SA, Preitner N. In vitro assessment of dietary bioactives for TFEB activation as a possible target to support cognitive and emotional wellbeing. J Funct Foods 111 (2023) 105855.
  2. Molnar-Kasza A, Hinteregger B, Neddens J, Rabl R, Flunkert S, Hutter-Paier B. Evaluation of Neuropathological Features in the SOD1-G93A Low Copy Number Transgenic Mouse Model of Amyotrophic Lateral Sclerosis. Front. Mol. Neurosci., 24 June 2021 PMID: 34248499.
  3.   Kurat S, Heinrich P, Molnar-Kasza A, Loeffler T, Flunkert S, Hutter-Paier B. Homozygosity of BACHD rats not only causes strong behavioral deficits in young female rats but also a reduced breeding success. Brain Res. 2021 Mar 1:147396. PMID: 33662341.
  4. Neddens J, Daurer M, Loeffler T, Alzola Aldamizetxebarria S, Flunkert S, Hutter-Paier B. Constant Levels of Tau Phosphorylation in the Brain of htau Mice. Front Mol Neurosci. 2020 Aug 28;13:136. PMID: 3298268.
  5.    Neddens J, Daurer M, Flunkert S, Beutl K, Loeffler T, Walker L, Attems J, Hutter-Paier B. Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer's disease and related murine models. PLoS One. 2020 Jul 9;15(7):e0235543. PMID: 32645028.
  6.    Loeffler T, Schilcher I, Flunkert S, Hutter-Paier B. Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value.Front Neurosci. 2020 Jun 11;14:579. PMID: 32595447.
  7.    Schiffer V, Santiago-Mujika E, Flunkert S, Schmidt S, Farcher M, Loeffler T, Schilcher I, Posch M, Neddens J, Sun Y, Kehr J, Hutter-Paier B. Characterization of the visceral and neuronal phenotype of 4L/PS-NA mice modeling Gaucher disease. PLoS One. 2020 Jan 13;15(1). PMID: 31929594.
  8.    Santiago-Mujica E, Flunkert S, Rabl R, Neddens J, Loeffler T, Hutter-Paier B. Hepatic and neuronal phenotype of NPC1-/- mice. Heliyon. 2019 Mar 14;5(3). PMID: 30923761.
  9.    Neddens J, Temmel M, Flunkert S, Kerschbaumer B, Hoeller C, Loeffler T, Niederkofler V, Daum G, Attems J, Hutter-Paier B. Phosphorylation of different tau sites during progression of Alzheimer's disease. Acta Neuropathol Commun. 2018 Jun 29;6(1). PMID: 29958544.
  10.    Brunner D, Flunkert S, Neddens J, Duller S, Scopes DIC, Treherne JM, Hutter-Paier B. SEN1500, a novel oral amyloid-β aggregation inhibitor, attenuates brain pathology in a mouse model of Alzheimer's disease. Neurosci Lett. 2017 Nov 1;660:96-102. PMID: 28917978.
  11.    Rabl R, Breitschaedel C, Flunkert S, Duller S, Amschl D, Neddens J, Niederkofler V, Rockenstein E, Masliah E, Roemer H, Hutter-Paier B. Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice. BMC Neurosci. 2017 Jan 31;18(1):22. PMID: 28143405.
  12.    Rabl R, Horvath A, Breitschaedel C, Flunkert S, Roemer H, Hutter-Paier B. Quantitative evaluation of orofacial motor function in mice: The pasta gnawing test, a voluntary and stress-free behavior test. J Neurosci Methods. 2016 Oct 13;274:125-130. PMID:27746230.
  13. Loeffler T, Flunkert S, Havas D, Schweinzer C, Uger M, Windisch M, Steyrer E, Hutter-Paier B. Neuroinflammation and related neuropathologies in APPPSL mice: further values of this in vivo model of Alzheimer’s disease. J Neroinflammation. 2014 May 1;11:84: PMID: 24886182.
  14. Windisch M, Flunkert S, Havas D, Hutter-Paier B. Commentary to the recently published review „Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease" by Li, Evrahimi and Schluesener. Ageing Res. Rev. 2013 Jan;12(1):116-40. Ageing Res Rev. 2013 Sep;12(4):852-4. PMID: 23851053.
  15. Amschl D, Neddens J, Havas D, Flunkert S, Rabl R, Roemer H, Rockenstein E, Masliah E, Windisch M, Hutter-Paier B. Time course and progression of wild type α-Synuclein accumulation in a transgenic mouse model. BMC Neurosci. 2013 Jan 9;14:6. PMID: 23302418.
  16.  Flunkert S, Hierzer M, Loeffler T, Rabl R, Neddens J, Duller S, Schofield EL, Ward MA, Posch M, Jungwirth H, Windisch M, Hutter-Paier B. Elevated Levels of Soluble Total and Hyperphosphorylated Tau Result in Early Behavioral Deficits and Distinct Changes in Brain Pathology in a New Tau Transgenic Mouse Model. Neurodegener Dis. 2012 Jul 10. PMID: 22797329.
  17. Loeffler T, Flunkert S, Taub N, Schofield EL, Ward MA, Windisch M, Hutter-Paier B. Stable mutated tau441 transfected SH-SY5Y cells as screening tool for Alzheimer's disease drug candidates. J Mol Neurosci. 2012 May;47(1):192-203. PMID: 22351109.

 

For a full list of publications see





Article

New Ground

Springer Medizin

DasGehirn.info


Events

  • Online-Seminar „Tipps & Tricks für die Erstellung deiner wissenschaftlichen Texte“ with Dr. Stefanie Flunkert. 10.06.2021, btS e.V. Ulm
  • Online Interview for Max Planck Career Evolution Web Series: From Science2Industry. 25.03.2021, Max Planck Society



Besides writing

My two personal welfare officers, Leo and Winny, take care that I regularly take a break:



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